The premise to Mother Knows Best reminds me of the 2009 horror movie Splice, in which two geneticists decide to mess with nature and create a human hybrid. The movie itself was disturbing and disappointing, but the message was clear: when men try to play God, it rarely ends well. It's a sci-fi horror lesson that has transcended countless films and books, from Jurassic Park to Frankenstein. We all know how the story ends, but we still want to read on to see how it unfolds.