Medical mystery turns into literary caper!

This is an unusual(!) book and it helped for me to read background and other reader/reviewer feedback to get some context prior to diving in. It's very cerebral (I learned new words and medical 'stuff') and found the author's style very 'literary' - perhaps like Richard Russo? It was a book within a book - the main character (Owen Berk) works for a literary magazine and his boss asks him to investigate the death of a prominent psychiatrist (related to the boss) who exploded on the table during a routine medical procedure. Owen decides to write a novel about the situation (hence book within a book) and the story alternates between the two. It covers a lot of ground - spirituality, mystery, medicine, humor, life's purpose, art, writing, dreams, skiing, etc. (what a range of topics!). It's going to appeal to a special type of reader.